Hiroshi Yamazaki Selected Research

1,2-dibromobenzene

12/2020

Different Hepatic Concentrations of Bromobenzene, 1,2-Dibromobenzene, and 1,4-Dibromobenzene in Humanized-Liver Mice Predicted Using Simplified Physiologically Based Pharmacokinetic Models as Putative Markers of Toxicological Potential.

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Hiroshi Yamazaki Research Topics

Disease

20	Neoplasms (Cancer) 09/2022 - 06/2002
17	Trimethylaminuria 12/2021 - 01/2003
10	Body Weight (Weight, Body) 10/2021 - 11/2003
6	Infections 07/2022 - 12/2009
5	Drug-Related Side Effects and Adverse Reactions 04/2022 - 01/2011
5	Multiple Myeloma 01/2021 - 01/2013
5	Squamous Cell Carcinoma of Head and Neck 10/2019 - 04/2011
4	Hearing Loss (Hearing Impairment) 04/2022 - 01/2018
4	Wounds and Injuries (Trauma) 12/2020 - 12/2009
4	Lung Neoplasms (Lung Cancer) 01/2017 - 12/2004
4	Atrioventricular Block 07/2015 - 01/2011
4	Long QT Syndrome 06/2015 - 01/2011
4	Neoplasm Metastasis (Metastasis) 01/2013 - 09/2002
3	False Aneurysm (Pseudoaneurysm) 09/2020 - 07/2015
3	Deafness (Deaf Mutism) 01/2020 - 01/2017
3	Respiratory Insufficiency (Respiratory Failure) 11/2019 - 01/2018
3	Torsades de Pointes (Torsade de Pointes) 01/2018 - 06/2015
3	Hepatocellular Carcinoma (Hepatoma) 09/2016 - 02/2002
3	Adenoma (Adenomas) 01/2012 - 11/2003
2	Breast Neoplasms (Breast Cancer) 08/2022 - 05/2015
2	Congenital Abnormalities (Deformity) 11/2021 - 09/2014
2	Colorectal Neoplasms (Colorectal Cancer) 10/2021 - 07/2021
2	Poisoning 08/2021 - 01/2020
2	Arteriosclerosis 06/2021 - 01/2020
2	Type 2 Diabetes Mellitus (MODY) 05/2021 - 04/2015
2	Drug Overdose 02/2021 - 01/2020
2	Liver Cirrhosis (Hepatic Cirrhosis) 12/2020 - 09/2020
2	Inborn Genetic Diseases (Disease, Hereditary) 08/2020 - 10/2019
2	Cough 01/2019 - 01/2018
2	Cysts 12/2017 - 05/2010
2	Parkinson Disease (Parkinson's Disease) 02/2017 - 06/2015
2	Leprosy (Hansen's Disease) 01/2017 - 01/2014
2	Atherosclerosis 01/2017 - 03/2015
2	Osteomyelitis 08/2014 - 11/2010
2	Carcinoma (Carcinomatosis) 01/2013 - 09/2002
2	Carcinogenesis 01/2012 - 11/2003
2	Rupture 05/2011 - 02/2010
2	Premature Cardiac Complexes (Extrasystoles) 01/2011 - 01/2011
2	Cardiac Arrhythmias (Arrythmia) 01/2011 - 01/2011
1	Hematologic Neoplasms (Hematological Malignancy) 09/2022
1	Knee Osteoarthritis 07/2022
1	Radius Fractures (Radius Fracture) 12/2021

Drug/Important Bio-Agent (IBA)

18	Pharmaceutical PreparationsIBA 04/2022 - 06/2002
17	dimethylaniline monooxygenase (N-oxide forming) (flavin-containing monooxygenase)IBA 12/2021 - 01/2003
13	trimethylamineIBA 06/2021 - 04/2004
10	EnzymesIBA 07/2021 - 06/2007
7	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 07/2021 - 12/2004
6	trimethyloxamine (trimethylamine N-oxide)IBA 06/2021 - 04/2004
4	Thalidomide (Thalomid)FDA Link 09/2022 - 01/2013
4	4- (N- methyl- N- nitrosamino)- 1- (3- pyridyl)- 1- butanoneIBA 01/2012 - 11/2003
3	Anti-Bacterial Agents (Antibiotics)IBA 07/2022 - 11/2010
3	(R)-2-(3-((benzoxazol-2-yl-d4 (3- (4- methoxyphenoxy- d7)propyl)amino)methyl)phenoxy) butanoic acidIBA 12/2020 - 07/2020
3	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 01/2007
3	Phosphates (Orthophosphate)IBA 11/2019 - 01/2018
3	dihydrocodeine FDA LinkGeneric 11/2019 - 01/2018
3	Glucose (Dextrose)FDA LinkGeneric 02/2012 - 08/2008
2	Lenalidomide (CC 5013)FDA Link 09/2022 - 05/2020
2	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 08/2022 - 09/2019
2	Proteins (Proteins, Gene)FDA Link 08/2022 - 10/2019
2	LY 165163 (PAPP)IBA 08/2022 - 10/2021
2	daratumumabIBA 01/2021 - 05/2020
2	Messenger RNA (mRNA)IBA 12/2020 - 10/2019
2	Dexamethasone (Maxidex)FDA LinkGeneric 05/2020 - 11/2011
2	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 04/2020 - 01/2018
2	Biomarkers (Surrogate Marker)IBA 01/2020 - 01/2018
2	edoxabanIBA 01/2020 - 09/2019
2	Nonsense Codon (Nonsense Mutation)IBA 10/2019 - 06/2007
2	AnticoagulantsIBA 09/2019 - 07/2016
2	Complementary DNA (cDNA)IBA 02/2017 - 12/2013
2	Hypnotics and Sedatives (Sedatives)IBA 01/2017 - 01/2014
2	Carnitine (L-Carnitine)FDA LinkGeneric 01/2017 - 03/2015
2	glutarimideIBA 01/2017 - 01/2014
2	Nicotine FDA Link 01/2017 - 01/2012
2	AntiemeticsIBA 01/2017 - 01/2014
2	Halothane (Fluothane)FDA Link 07/2015 - 06/2015
2	SteroidsIBA 05/2015 - 11/2011
2	Cytochrome P-450 CYP3AIBA 05/2015 - 02/2004
2	OxidesIBA 05/2014 - 06/2007
2	Sotalol (Sotalol Hydrochloride)FDA LinkGeneric 01/2011 - 01/2011
2	Capsules (Microcapsules)IBA 02/2010 - 06/2002
2	Methoxsalen (Oxsoralen)FDA Link 11/2005 - 11/2003
2	TegafurIBA 09/2005 - 06/2002
1	Pregnancy-Associated Plasma Protein-A (PAPP-A)IBA 08/2022
1	Oxazolidinones (2 Oxazolidone)IBA 07/2022
1	Linezolid (Zyvox)FDA Link 07/2022

Therapy/Procedure

10	Therapeutics 01/2021 - 09/2005
6	Oral Administration 12/2020 - 09/2005
5	Cochlear Implantation 04/2022 - 04/2012
4	Cochlear Implants (Cochlear Implant) 01/2020 - 04/2012
4	Intravenous Administration 06/2015 - 05/2009
4	Drug Therapy (Chemotherapy) 01/2013 - 05/2009
3	Nephrectomy 09/2020 - 07/2015
3	Neck Dissection (Radical Neck Dissection) 06/2012 - 09/2002
3	Radiotherapy 11/2011 - 12/2009
3	Tracheostomy 01/2011 - 04/2009
2	Renal Dialysis (Hemodialysis) 03/2015 - 05/2007
2	Tympanoplasty 02/2014 - 03/2012
2	Neoadjuvant Therapy 06/2013 - 04/2011
2	Glossectomy 06/2012 - 09/2002
1	Intravenous Infusions 07/2022